Skip to content
GitLab
Menu
Projects
Groups
Snippets
Loading...
Help
Help
Support
Community forum
Keyboard shortcuts
?
Submit feedback
Contribute to GitLab
Sign in / Register
Toggle navigation
Menu
Open sidebar
ModelZoo
CIRI-deep_tensorflow
Commits
f8f189bf
Commit
f8f189bf
authored
Dec 05, 2024
by
wangsen
Browse files
change readme.md
parent
31584347
Changes
1
Hide whitespace changes
Inline
Side-by-side
Showing
1 changed file
with
11 additions
and
19 deletions
+11
-19
README.md
README.md
+11
-19
No files found.
README.md
View file @
f8f189bf
# cirideep
# 论文
## 论文
CIRI-Deep Enables Single-Cell and Spatial Transcriptomic Analysis of Circular RNAs with Deep Learning
https://onlinelibrary.wiley.com/doi/10.1002/advs.202308115
# 模型结构
#
# 模型结构
CIRI-deep模型可有效用于各转录组样本间推断差异剪接环形RNA,拓展了环形RNA的研究范围,为环形RNA研究提供了新的高效分析方法。同时,CIRI-deepA模型可以提供单细胞及空间水平环形RNA的有效解析,

# 算法原理
#
# 算法原理
CIRI deep通过深度神经网络对circRNA的顺式特征和样本对(总RNA或富含poly(A)的RNA)的RBP表达进行训练。

# 环境配置
## Docker(方法一)
#
# 环境配置
##
#
Docker(方法一)
```
docker pull image.sourcefind.cn:5000/dcu/admin/base/custom:cirideep
...
...
@@ -29,16 +29,8 @@ docker run -dit --shm-size 80g --network=host --name=CIRI --privileged --device=
docker exec -it CIRI /bin/bash
```
安装依赖
```
pip install ./whl/tensorflow-1.15.1+git06e2e8aa.dtk2404-cp37-cp37m-linux_x86_64.whl
pip install -r requirements.txt -i http://mirrors.aliyun.com/pypi/simple/ --trusted-host mirrors.aliyun.com
```
## Dockerfile(方法二)
##
#
Dockerfile(方法二)
```
docker build -t cirideep:latest .
...
...
@@ -46,7 +38,7 @@ docker run -dit --shm-size 80g --network=host --name=CIRI --privileged --device=
docker exec -it CIRI /bin/bash
```
## anaconda (方法三)
##
#
anaconda (方法三)
1.
创建conda虚拟环境:
...
...
@@ -63,10 +55,10 @@ pip install -r requirements.txt -i http://mirrors.aliyun.com/pypi/simple/ --trus
```
#
预测
#
#
推理
##
用CIRI-deep进行预测
##
# 使
用CIRI-deep进行预测
```
python CIRIdeep.py predict -geneExp_absmax ./demo/RBPmax_totalRNA.tsv -seqFeature ./demo/cisfeature.tsv -splicing_max ./demo/splicingamount_max.tsv -predict_list ./demo/predict_list.txt -model_path ./models/CIRIdeep.h5 -outdir ./outdir -RBP_dir ./demo/RBPexp_total -splicing_dir ./demo/splicingamount
```
...
...
@@ -77,7 +69,7 @@ python CIRIdeep.py predict -geneExp_absmax ./demo/RBPmax_totalRNA.tsv -seqFeatur
## 用CIRI-deepA进行预测
##
#
用CIRI-deepA进行预测
```
python CIRIdeep.py predict -geneExp_absmax ./demo/RBPmax_polyA.tsv -seqFeature ./demo/cisfeature.tsv -predict_list ./demo/predict_list.txt -model_path ./models/CIRIdeepA.h5 -outdir ./outdir -RBP_dir ./demo/RBPexp_polyA --CIRIdeepA
...
...
Write
Preview
Markdown
is supported
0%
Try again
or
attach a new file
.
Attach a file
Cancel
You are about to add
0
people
to the discussion. Proceed with caution.
Finish editing this message first!
Cancel
Please
register
or
sign in
to comment