Commit ac79672c authored by Gustaf Ahdritz's avatar Gustaf Ahdritz
Browse files

Clarify dependencies in README

parent 220f49e0
......@@ -24,8 +24,9 @@ future.
Python dependencies available through `pip` are provided in `requirements.txt`.
OpenFold depends on `openmm==7.5.1` and `pdbfixer`, which are only available
via `conda`. For producing sequence alignments, you'll also need `jackhmmer`,
`kalign`, and the [HH-suite](https://github.com/soedinglab/hh-suite) installed
via `conda`. For producing sequence alignments, you'll also need
`kalign`, the [HH-suite](https://github.com/soedinglab/hh-suite), and one of
{`jackhmmer`, [MMseqs2](https://github.com/soedinglab/mmseqs2)} installed on
on your system. Finally, some download scripts require `aria2c`.
For convenience, we provide a script that installs Miniconda locally, creates a
......@@ -65,7 +66,7 @@ scripts/download_data.sh data/
You have two choices for downloading protein databases, depending on whether
you want to use DeepMind's MSA generation pipeline (w/ HMMR & HHblits) or
[ColabFold](https://github.com/sokrypton/ColabFold)'s, which uses the faster
[MMseqs2](https://github.com/soedinglab/mmseqs2) instead. For the former, run:
MMseqs2 instead. For the former, run:
```bash
scripts/download_alphafold_databases.sh data/
......
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