<ForceField>
 <Info>
    <DateGenerated>2017-11-25</DateGenerated>
    <Source Source="parm/frcmod.ionsjc_tip3p" md5hash="0e5e74a17e42382511afd4116f70ff16" sourcePackage="AmberTools" sourcePackageVersion="17">parm/frcmod.ionsjc_tip3p</Source>
    <Source Source="parm/frcmod.ions234lm_126_tip3p" md5hash="69bb41a7702e76fb9f5ef041d063dfae" sourcePackage="AmberTools" sourcePackageVersion="17">parm/frcmod.ions234lm_126_tip3p</Source>
    <Source Source="lib/atomic_ions.lib" md5hash="e900cee0c71ec2795d25b3555de486e1" sourcePackage="AmberTools" sourcePackageVersion="17">lib/atomic_ions.lib</Source>
    <Source Source="tip3p.xml" md5hash="dde8c717e8d77c7511b575779ac9f968" sourcePackage="OpenMM" sourcePackageVersion="7.2">tip3p.xml</Source>
    <Reference>Joung, I.S., and Cheatham, Thomas E. (2008). Determination of Alkali and Halide Monovalent Ion Parameters for Use in Explicitly Solvated Biomolecular Simulations. J. Phys. Chem. B 112, 9020-9041.</Reference>
    <Reference>Joung, I.S., and Cheatham, T.E. (2009). Molecular Dynamics Simulations of the Dynamic and Energetic Properties of Alkali and Halide Ions Using Water-Model-Specific Ion Parameters. J. Phys. Chem. B 113, 13279-13290.</Reference>
    <Reference>Li, P., Roberts, B.P., Chakravorty, D.K., and Merz, K.M. (2013). Rational Design of Particle Mesh Ewald Compatible Lennard-Jones Parameters for +2 Metal Cations in Explicit Solvent. J. Chem. Theory Comput. 9, 2733-2748.</Reference>
    <Reference>Jorgensen, W.L., Chandrasekhar, J., Madura, J.D., Impey, R.W., and Klein, M.L. (1983). Comparison of simple potential functions for simulating liquid water. The Journal of Chemical Physics 79, 926-935.</Reference>
  </Info>
  <AtomTypes>
  <Type class="tip3p_standard-Li+" element="Li" mass="6.94" name="tip3p_standard-Li+"/>
    <Type class="tip3p_standard-Na+" element="Na" mass="22.99" name="tip3p_standard-Na+"/>
    <Type class="tip3p_standard-K+" element="K" mass="39.1" name="tip3p_standard-K+"/>
    <Type class="tip3p_standard-Rb+" element="Rb" mass="85.47" name="tip3p_standard-Rb+"/>
    <Type class="tip3p_standard-Cs+" element="Cs" mass="132.91" name="tip3p_standard-Cs+"/>
    <Type class="tip3p_standard-F-" element="F" mass="19.0" name="tip3p_standard-F-"/>
    <Type class="tip3p_standard-Cl-" element="Cl" mass="35.45" name="tip3p_standard-Cl-"/>
    <Type class="tip3p_standard-Br-" element="Br" mass="79.9" name="tip3p_standard-Br-"/>
    <Type class="tip3p_standard-I-" element="I" mass="126.9" name="tip3p_standard-I-"/>
    <Type class="tip3p_standard-Be2+" element="Be" mass="9.01" name="tip3p_standard-Be2+"/>
    <Type class="tip3p_standard-Cu2+" element="Cu" mass="63.55" name="tip3p_standard-Cu2+"/>
    <Type class="tip3p_standard-Ni2+" element="Ni" mass="58.69" name="tip3p_standard-Ni2+"/>
    <Type class="tip3p_standard-Pt2+" element="Pt" mass="195.08" name="tip3p_standard-Pt2+"/>
    <Type class="tip3p_standard-Zn2+" element="Zn" mass="65.4" name="tip3p_standard-Zn2+"/>
    <Type class="tip3p_standard-Co2+" element="Co" mass="58.93" name="tip3p_standard-Co2+"/>
    <Type class="tip3p_standard-Pd2+" element="Pd" mass="106.42" name="tip3p_standard-Pd2+"/>
    <Type class="tip3p_standard-Ag2+" element="Ag" mass="107.87" name="tip3p_standard-Ag2+"/>
    <Type class="tip3p_standard-Cr2+" element="Cr" mass="52.0" name="tip3p_standard-Cr2+"/>
    <Type class="tip3p_standard-Fe2+" element="Fe" mass="55.85" name="tip3p_standard-Fe2+"/>
    <Type class="tip3p_standard-Mg2+" element="Mg" mass="24.305" name="tip3p_standard-Mg2+"/>
    <Type class="tip3p_standard-V2+" element="V" mass="50.94" name="tip3p_standard-V2+"/>
    <Type class="tip3p_standard-Mn2+" element="Mn" mass="54.94" name="tip3p_standard-Mn2+"/>
    <Type class="tip3p_standard-Hg2+" element="Hg" mass="200.59" name="tip3p_standard-Hg2+"/>
    <Type class="tip3p_standard-Cd2+" element="Cd" mass="112.41" name="tip3p_standard-Cd2+"/>
    <Type class="tip3p_standard-Yb2+" element="Yb" mass="173.05" name="tip3p_standard-Yb2+"/>
    <Type class="tip3p_standard-Ca2+" element="Ca" mass="40.08" name="tip3p_standard-Ca2+"/>
    <Type class="tip3p_standard-Sn2+" element="Sn" mass="118.71" name="tip3p_standard-Sn2+"/>
    <Type class="tip3p_standard-Pb2+" element="Pb" mass="207.2" name="tip3p_standard-Pb2+"/>
    <Type class="tip3p_standard-Eu2+" element="Eu" mass="151.96" name="tip3p_standard-Eu2+"/>
    <Type class="tip3p_standard-Sr2+" element="Sr" mass="87.62" name="tip3p_standard-Sr2+"/>
    <Type class="tip3p_standard-Sm2+" element="Sm" mass="150.36" name="tip3p_standard-Sm2+"/>
    <Type class="tip3p_standard-Ba2+" element="Ba" mass="137.33" name="tip3p_standard-Ba2+"/>
    <Type class="tip3p_standard-Ra2+" element="Ra" mass="226.03" name="tip3p_standard-Ra2+"/>
    <Type class="tip3p_standard-Al3+" element="Al" mass="26.98" name="tip3p_standard-Al3+"/>
    <Type class="tip3p_standard-Fe3+" element="Fe" mass="55.85" name="tip3p_standard-Fe3+"/>
    <Type class="tip3p_standard-Cr3+" element="Cr" mass="52.0" name="tip3p_standard-Cr3+"/>
    <Type class="tip3p_standard-In3+" element="In" mass="114.82" name="tip3p_standard-In3+"/>
    <Type class="tip3p_standard-Tl3+" element="Tl" mass="204.38" name="tip3p_standard-Tl3+"/>
    <Type class="tip3p_standard-Y3+" element="Y" mass="88.91" name="tip3p_standard-Y3+"/>
    <Type class="tip3p_standard-La3+" element="La" mass="138.91" name="tip3p_standard-La3+"/>
    <Type class="tip3p_standard-Ce3+" element="Ce" mass="140.12" name="tip3p_standard-Ce3+"/>
    <Type class="tip3p_standard-Pr3+" element="Pr" mass="140.91" name="tip3p_standard-Pr3+"/>
    <Type class="tip3p_standard-Nd3+" element="Nd" mass="144.24" name="tip3p_standard-Nd3+"/>
    <Type class="tip3p_standard-Sm3+" element="Sm" mass="150.36" name="tip3p_standard-Sm3+"/>
    <Type class="tip3p_standard-Eu3+" element="Eu" mass="151.96" name="tip3p_standard-Eu3+"/>
    <Type class="tip3p_standard-Gd3+" element="Gd" mass="157.25" name="tip3p_standard-Gd3+"/>
    <Type class="tip3p_standard-Tb3+" element="Tb" mass="158.93" name="tip3p_standard-Tb3+"/>
    <Type class="tip3p_standard-Dy3+" element="Dy" mass="162.5" name="tip3p_standard-Dy3+"/>
    <Type class="tip3p_standard-Er3+" element="Er" mass="167.26" name="tip3p_standard-Er3+"/>
    <Type class="tip3p_standard-Tm3+" element="Tm" mass="168.93" name="tip3p_standard-Tm3+"/>
    <Type class="tip3p_standard-Lu3+" element="Lu" mass="174.97" name="tip3p_standard-Lu3+"/>
    <Type class="tip3p_standard-Hf4+" element="Hf" mass="178.49" name="tip3p_standard-Hf4+"/>
    <Type class="tip3p_standard-Zr4+" element="Zr" mass="91.22" name="tip3p_standard-Zr4+"/>
    <Type class="tip3p_standard-Ce4+" element="Ce" mass="140.12" name="tip3p_standard-Ce4+"/>
    <Type class="tip3p_standard-U4+" element="U" mass="238.03" name="tip3p_standard-U4+"/>
    <Type class="tip3p_standard-Pu4+" element="Pu" mass="244.06" name="tip3p_standard-Pu4+"/>
    <Type class="tip3p_standard-Th4+" element="Th" mass="232.04" name="tip3p_standard-Th4+"/>
   <Type name="tip3p-O" class="tip3p-O" element="O" mass="15.99943"/>
  <Type name="tip3p-H" class="tip3p-H" element="H" mass="1.007947"/>
 </AtomTypes>
 <Residues>
  <Residue name="AL">
      <Atom charge="3.0" name="AL" type="tip3p_standard-Al3+"/>
    </Residue>
    <Residue name="Ag">
      <Atom charge="2.0" name="Ag" type="tip3p_standard-Ag2+"/>
    </Residue>
    <Residue name="BA">
      <Atom charge="2.0" name="BA" type="tip3p_standard-Ba2+"/>
    </Residue>
    <Residue name="BR">
      <Atom charge="-1.0" name="BR" type="tip3p_standard-Br-"/>
    </Residue>
    <Residue name="Be">
      <Atom charge="2.0" name="Be" type="tip3p_standard-Be2+"/>
    </Residue>
    <Residue name="CA">
      <Atom charge="2.0" name="CA" type="tip3p_standard-Ca2+"/>
    </Residue>
    <Residue name="CD">
      <Atom charge="2.0" name="CD" type="tip3p_standard-Cd2+"/>
    </Residue>
    <Residue name="CE">
      <Atom charge="3.0" name="CE" type="tip3p_standard-Ce3+"/>
    </Residue>
    <Residue name="CL">
      <Atom charge="-1.0" name="CL" type="tip3p_standard-Cl-"/>
    </Residue>
    <Residue name="CO">
      <Atom charge="2.0" name="CO" type="tip3p_standard-Co2+"/>
    </Residue>
    <Residue name="CR">
      <Atom charge="3.0" name="CR" type="tip3p_standard-Cr3+"/>
    </Residue>
    <Residue name="CS">
      <Atom charge="1.0" name="CS" type="tip3p_standard-Cs+"/>
    </Residue>
    <Residue name="CU">
      <Atom charge="2.0" name="CU" type="tip3p_standard-Cu2+"/>
    </Residue>
    <Residue name="Ce">
      <Atom charge="4.0" name="Ce" type="tip3p_standard-Ce4+"/>
    </Residue>
    <Residue name="Cr">
      <Atom charge="2.0" name="Cr" type="tip3p_standard-Cr2+"/>
    </Residue>
    <Residue name="Dy">
      <Atom charge="3.0" name="Dy" type="tip3p_standard-Dy3+"/>
    </Residue>
    <Residue name="EU">
      <Atom charge="2.0" name="EU" type="tip3p_standard-Eu2+"/>
    </Residue>
    <Residue name="EU3">
      <Atom charge="3.0" name="EU3" type="tip3p_standard-Eu3+"/>
    </Residue>
    <Residue name="Er">
      <Atom charge="3.0" name="Er" type="tip3p_standard-Er3+"/>
    </Residue>
    <Residue name="F">
      <Atom charge="-1.0" name="F" type="tip3p_standard-F-"/>
    </Residue>
    <Residue name="FE">
      <Atom charge="3.0" name="FE" type="tip3p_standard-Fe3+"/>
    </Residue>
    <Residue name="FE2">
      <Atom charge="2.0" name="FE2" type="tip3p_standard-Fe2+"/>
    </Residue>
    <Residue name="GD3">
      <Atom charge="3.0" name="GD" type="tip3p_standard-Gd3+"/>
    </Residue>
    <Residue name="HG">
      <Atom charge="2.0" name="HG" type="tip3p_standard-Hg2+"/>
    </Residue>
    <Residue name="Hf">
      <Atom charge="4.0" name="Hf" type="tip3p_standard-Hf4+"/>
    </Residue>
    <Residue name="IN">
      <Atom charge="3.0" name="IN" type="tip3p_standard-In3+"/>
    </Residue>
    <Residue name="IOD">
      <Atom charge="-1.0" name="I" type="tip3p_standard-I-"/>
    </Residue>
    <Residue name="K">
      <Atom charge="1.0" name="K" type="tip3p_standard-K+"/>
    </Residue>
    <Residue name="LA">
      <Atom charge="3.0" name="LA" type="tip3p_standard-La3+"/>
    </Residue>
    <Residue name="LI">
      <Atom charge="1.0" name="LI" type="tip3p_standard-Li+"/>
    </Residue>
    <Residue name="LU">
      <Atom charge="3.0" name="LU" type="tip3p_standard-Lu3+"/>
    </Residue>
    <Residue name="MG">
      <Atom charge="2.0" name="MG" type="tip3p_standard-Mg2+"/>
    </Residue>
    <Residue name="MN">
      <Atom charge="2.0" name="MN" type="tip3p_standard-Mn2+"/>
    </Residue>
    <Residue name="NA">
      <Atom charge="1.0" name="NA" type="tip3p_standard-Na+"/>
    </Residue>
    <Residue name="NI">
      <Atom charge="2.0" name="NI" type="tip3p_standard-Ni2+"/>
    </Residue>
    <Residue name="Nd">
      <Atom charge="3.0" name="Nd" type="tip3p_standard-Nd3+"/>
    </Residue>
    <Residue name="PB">
      <Atom charge="2.0" name="PB" type="tip3p_standard-Pb2+"/>
    </Residue>
    <Residue name="PD">
      <Atom charge="2.0" name="PD" type="tip3p_standard-Pd2+"/>
    </Residue>
    <Residue name="PR">
      <Atom charge="3.0" name="PR" type="tip3p_standard-Pr3+"/>
    </Residue>
    <Residue name="PT">
      <Atom charge="2.0" name="PT" type="tip3p_standard-Pt2+"/>
    </Residue>
    <Residue name="Pu">
      <Atom charge="4.0" name="Pu" type="tip3p_standard-Pu4+"/>
    </Residue>
    <Residue name="RB">
      <Atom charge="1.0" name="RB" type="tip3p_standard-Rb+"/>
    </Residue>
    <Residue name="Ra">
      <Atom charge="2.0" name="Ra" type="tip3p_standard-Ra2+"/>
    </Residue>
    <Residue name="SM">
      <Atom charge="3.0" name="SM" type="tip3p_standard-Sm3+"/>
    </Residue>
    <Residue name="SR">
      <Atom charge="2.0" name="SR" type="tip3p_standard-Sr2+"/>
    </Residue>
    <Residue name="Sm">
      <Atom charge="2.0" name="Sm" type="tip3p_standard-Sm2+"/>
    </Residue>
    <Residue name="Sn">
      <Atom charge="2.0" name="Sn" type="tip3p_standard-Sn2+"/>
    </Residue>
    <Residue name="TB">
      <Atom charge="3.0" name="TB" type="tip3p_standard-Tb3+"/>
    </Residue>
    <Residue name="Th">
      <Atom charge="4.0" name="Th" type="tip3p_standard-Th4+"/>
    </Residue>
    <Residue name="Tl">
      <Atom charge="3.0" name="Tl" type="tip3p_standard-Tl3+"/>
    </Residue>
    <Residue name="Tm">
      <Atom charge="3.0" name="Tm" type="tip3p_standard-Tm3+"/>
    </Residue>
    <Residue name="U4+">
      <Atom charge="4.0" name="U" type="tip3p_standard-U4+"/>
    </Residue>
    <Residue name="V2+">
      <Atom charge="2.0" name="V2+" type="tip3p_standard-V2+"/>
    </Residue>
    <Residue name="Y">
      <Atom charge="3.0" name="Y" type="tip3p_standard-Y3+"/>
    </Residue>
    <Residue name="YB2">
      <Atom charge="2.0" name="YB2" type="tip3p_standard-Yb2+"/>
    </Residue>
    <Residue name="ZN">
      <Atom charge="2.0" name="ZN" type="tip3p_standard-Zn2+"/>
    </Residue>
    <Residue name="Zr">
      <Atom charge="4.0" name="Zr" type="tip3p_standard-Zr4+"/>
    </Residue>
   <Residue name="HOH">
   <Atom name="O" type="tip3p-O" charge="-0.834"/>
   <Atom name="H1" type="tip3p-H" charge="0.417"/>
   <Atom name="H2" type="tip3p-H" charge="0.417"/>
   <Bond atomName1="O" atomName2="H1"/>
   <Bond atomName1="O" atomName2="H2"/>
  </Residue>
 </Residues>
 <HarmonicBondForce>
  <Bond type1="tip3p-O" type2="tip3p-H" length="0.09572" k="462750.4"/>
 </HarmonicBondForce>
 <HarmonicAngleForce>
  <Angle type1="tip3p-H" type2="tip3p-O" type3="tip3p-H" angle="1.82421813418" k="836.8"/>
 </HarmonicAngleForce>
 <NonbondedForce coulomb14scale="0.8333333333333334" lj14scale="0.5">
  <UseAttributeFromResidue name="charge"/>
    <Atom epsilon="0.1171084864" sigma="0.18263423721876956" type="tip3p_standard-Li+"/>
    <Atom epsilon="0.3658460312" sigma="0.2439280690268249" type="tip3p_standard-Na+"/>
    <Atom epsilon="0.8103692536" sigma="0.3037964628858557" type="tip3p_standard-K+"/>
    <Atom epsilon="1.3716068296000001" sigma="0.32303987519768707" type="tip3p_standard-Rb+"/>
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    <Atom epsilon="0.014074976" sigma="0.4103479495754403" type="tip3p_standard-F-"/>
    <Atom epsilon="0.14891274399999999" sigma="0.4477656957373345" type="tip3p_standard-Cl-"/>
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    <Atom epsilon="1.6526800000000002e-05" sigma="0.17033983490843285" type="tip3p_standard-Be2+"/>
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    <Atom epsilon="0.021335931440000004" sigma="0.23216820594737242" type="tip3p_standard-Pd2+"/>
    <Atom epsilon="0.032257342960000004" sigma="0.2380481374870987" type="tip3p_standard-Ag2+"/>
    <Atom epsilon="0.03632456752" sigma="0.23982993492337937" type="tip3p_standard-Cr2+"/>
    <Atom epsilon="0.03940482832" sigma="0.24107719312877582" type="tip3p_standard-Fe2+"/>
    <Atom epsilon="0.042686716080000006" sigma="0.2423244513341723" type="tip3p_standard-Mg2+"/>
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    <Atom epsilon="0.0705719464" sigma="0.25069889928469147" type="tip3p_standard-Mn2+"/>
    <Atom epsilon="0.0705719464" sigma="0.25069889928469147" type="tip3p_standard-Hg2+"/>
    <Atom epsilon="0.07419972544" sigma="0.2515897980028318" type="tip3p_standard-Cd2+"/>
    <Atom epsilon="0.426181194" sigma="0.29257113903728743" type="tip3p_standard-Yb2+"/>
    <Atom epsilon="0.4432056808" sigma="0.29381839724268394" type="tip3p_standard-Ca2+"/>
    <Atom epsilon="0.48608615792" sigma="0.29684745288436104" type="tip3p_standard-Sn2+"/>
    <Atom epsilon="0.71203621616" sigma="0.31092365263097843" type="tip3p_standard-Pb2+"/>
    <Atom epsilon="0.8985523254400001" sigma="0.3210798980177783" type="tip3p_standard-Eu2+"/>
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    <Atom epsilon="1.7014071987200001" sigma="0.35974490238506907" type="tip3p_standard-Ba2+"/>
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    <Atom epsilon="0.27501557520000003" sigma="0.2799203772396946" type="tip3p_standard-Tl3+"/>
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    <Atom epsilon="0.83118754056" sigma="0.31751630314521695" type="tip3p_standard-Ce3+"/>
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    <Atom epsilon="0.77874118424" sigma="0.31466542724716784" type="tip3p_standard-Ce4+"/>
    <Atom epsilon="0.8646299178400001" sigma="0.31929810058149766" type="tip3p_standard-U4+"/>
    <Atom epsilon="0.73399083568" sigma="0.3121709108363749" type="tip3p_standard-Pu4+"/>
    <Atom epsilon="0.7917259353600001" sigma="0.31537814622168014" type="tip3p_standard-Th4+"/>
   <Atom type="tip3p-O" sigma="0.31507524065751241" epsilon="0.635968"/>
  <Atom type="tip3p-H" sigma="1" epsilon="0"/>
 </NonbondedForce>
</ForceField>