[["Abstract: The use of open access endoscopy is increasing. Its effect on the adequacy of patient informed consent, procedure acceptance and the impact on subsequent communication/transfer of procedure results to the patient have not been evaluated. The aim of our study was to compare the extent of preknowledge of procedures and test explanation, patient medical complexity, information transfer and overall patient satisfaction between a patient group referred for outpatient open access endoscopy versus a patient group from a gastrointestinal (GI) subspecialty clinic.\nInformation was obtained from all patients presenting for outpatient upper and lower endoscopy by using a 1-page questionnaire. Patients from the two groups who had an outpatient upper/lower endoscopic procedure were contacted by phone after the procedure to obtain information with a standardized questionnaire.\nThe open access patients reported receiving significantly less information to help them identify the procedure (p<0.01) and less explanation concerning the nature of the procedure than the group of patients referred from the subspecialty clinic (p<0.005). There was no difference between the two groups in satisfaction scores for examinations performed under conscious sedation. For flexible sigmoidoscopy without sedation, however, the GI clinic patient group were more satisfied with their procedure. The majority of patients, regardless of access, were more likely to receive endoscopic results from a gastroenterologist than the referring physician. Furthermore, the patients in the GI clinic group who underwent colonoscopy felt significantly better at follow-up.\nQuestion: Does open access endoscopy close the door to an adequately informed patient?\nAnswer:", " yes"], ["Abstract: The use of open access endoscopy is increasing. Its effect on the adequacy of patient informed consent, procedure acceptance and the impact on subsequent communication/transfer of procedure results to the patient have not been evaluated. The aim of our study was to compare the extent of preknowledge of procedures and test explanation, patient medical complexity, information transfer and overall patient satisfaction between a patient group referred for outpatient open access endoscopy versus a patient group from a gastrointestinal (GI) subspecialty clinic.\nInformation was obtained from all patients presenting for outpatient upper and lower endoscopy by using a 1-page questionnaire. Patients from the two groups who had an outpatient upper/lower endoscopic procedure were contacted by phone after the procedure to obtain information with a standardized questionnaire.\nThe open access patients reported receiving significantly less information to help them identify the procedure (p<0.01) and less explanation concerning the nature of the procedure than the group of patients referred from the subspecialty clinic (p<0.005). There was no difference between the two groups in satisfaction scores for examinations performed under conscious sedation. For flexible sigmoidoscopy without sedation, however, the GI clinic patient group were more satisfied with their procedure. The majority of patients, regardless of access, were more likely to receive endoscopic results from a gastroenterologist than the referring physician. Furthermore, the patients in the GI clinic group who underwent colonoscopy felt significantly better at follow-up.\nQuestion: Does open access endoscopy close the door to an adequately informed patient?\nAnswer:", " no"], ["Abstract: The use of open access endoscopy is increasing. Its effect on the adequacy of patient informed consent, procedure acceptance and the impact on subsequent communication/transfer of procedure results to the patient have not been evaluated. The aim of our study was to compare the extent of preknowledge of procedures and test explanation, patient medical complexity, information transfer and overall patient satisfaction between a patient group referred for outpatient open access endoscopy versus a patient group from a gastrointestinal (GI) subspecialty clinic.\nInformation was obtained from all patients presenting for outpatient upper and lower endoscopy by using a 1-page questionnaire. Patients from the two groups who had an outpatient upper/lower endoscopic procedure were contacted by phone after the procedure to obtain information with a standardized questionnaire.\nThe open access patients reported receiving significantly less information to help them identify the procedure (p<0.01) and less explanation concerning the nature of the procedure than the group of patients referred from the subspecialty clinic (p<0.005). There was no difference between the two groups in satisfaction scores for examinations performed under conscious sedation. For flexible sigmoidoscopy without sedation, however, the GI clinic patient group were more satisfied with their procedure. The majority of patients, regardless of access, were more likely to receive endoscopic results from a gastroenterologist than the referring physician. Furthermore, the patients in the GI clinic group who underwent colonoscopy felt significantly better at follow-up.\nQuestion: Does open access endoscopy close the door to an adequately informed patient?\nAnswer:", " maybe"], ["Abstract: To examine the evidence base of sports medicine research and assess how relevant and applicable it is to everyday practice.\nOriginal research articles, short reports, and case reports published in four major sport and exercise medicine journals were studied and classified according to the main topic of study and type of subjects used.\nThe most common topic was sports science, and very few studies related to the treatment of injuries and medical conditions. The majority of published articles used healthy subjects sampled from the sedentary population, and few studies have been carried out on injured participants.\nQuestion: Are sports medicine journals relevant and applicable to practitioners and athletes?\nAnswer:", " yes"], ["Abstract: To examine the evidence base of sports medicine research and assess how relevant and applicable it is to everyday practice.\nOriginal research articles, short reports, and case reports published in four major sport and exercise medicine journals were studied and classified according to the main topic of study and type of subjects used.\nThe most common topic was sports science, and very few studies related to the treatment of injuries and medical conditions. The majority of published articles used healthy subjects sampled from the sedentary population, and few studies have been carried out on injured participants.\nQuestion: Are sports medicine journals relevant and applicable to practitioners and athletes?\nAnswer:", " no"], ["Abstract: To examine the evidence base of sports medicine research and assess how relevant and applicable it is to everyday practice.\nOriginal research articles, short reports, and case reports published in four major sport and exercise medicine journals were studied and classified according to the main topic of study and type of subjects used.\nThe most common topic was sports science, and very few studies related to the treatment of injuries and medical conditions. The majority of published articles used healthy subjects sampled from the sedentary population, and few studies have been carried out on injured participants.\nQuestion: Are sports medicine journals relevant and applicable to practitioners and athletes?\nAnswer:", " maybe"], ["Abstract: To evaluate the effectiveness of feeding information on pharmacy back to primary care doctors in order to create awareness (knowledge) of pharmaceutical expenditure (PE).\nRetrospective cross-sectional study, through personal interview.\nReformed PC, Sabadell, Barcelona.\nThe 80 PC doctors working with primary care teams.\nAs the personal feed-back on PE, each doctor was asked for the PE generated during 1997 and the mean cost of prescriptions to active and pensioner patients. The statistical test used was the t test to compare means for paired data, with p<0.05 the required level of significance.\nOut of the total doctors interviewed (80), 71 replies were obtained for the annual PE and 76 for the mean cost of prescriptions, for both active and pensioner patients. Significant differences were found between the annual PE in reality and doctors' estimates: around twelve million pesetas. The differences between the real mean costs of prescription and the estimates were also significant.\nQuestion: Is there awareness of pharmaceutical expenditure in the reformed primary care system?\nAnswer:", " yes"], ["Abstract: To evaluate the effectiveness of feeding information on pharmacy back to primary care doctors in order to create awareness (knowledge) of pharmaceutical expenditure (PE).\nRetrospective cross-sectional study, through personal interview.\nReformed PC, Sabadell, Barcelona.\nThe 80 PC doctors working with primary care teams.\nAs the personal feed-back on PE, each doctor was asked for the PE generated during 1997 and the mean cost of prescriptions to active and pensioner patients. The statistical test used was the t test to compare means for paired data, with p<0.05 the required level of significance.\nOut of the total doctors interviewed (80), 71 replies were obtained for the annual PE and 76 for the mean cost of prescriptions, for both active and pensioner patients. Significant differences were found between the annual PE in reality and doctors' estimates: around twelve million pesetas. The differences between the real mean costs of prescription and the estimates were also significant.\nQuestion: Is there awareness of pharmaceutical expenditure in the reformed primary care system?\nAnswer:", " no"], ["Abstract: To evaluate the effectiveness of feeding information on pharmacy back to primary care doctors in order to create awareness (knowledge) of pharmaceutical expenditure (PE).\nRetrospective cross-sectional study, through personal interview.\nReformed PC, Sabadell, Barcelona.\nThe 80 PC doctors working with primary care teams.\nAs the personal feed-back on PE, each doctor was asked for the PE generated during 1997 and the mean cost of prescriptions to active and pensioner patients. The statistical test used was the t test to compare means for paired data, with p<0.05 the required level of significance.\nOut of the total doctors interviewed (80), 71 replies were obtained for the annual PE and 76 for the mean cost of prescriptions, for both active and pensioner patients. Significant differences were found between the annual PE in reality and doctors' estimates: around twelve million pesetas. The differences between the real mean costs of prescription and the estimates were also significant.\nQuestion: Is there awareness of pharmaceutical expenditure in the reformed primary care system?\nAnswer:", " maybe"], ["Abstract: A multicentre, retrospective study was conducted of patients with rectal cancer threatening or affecting the prostatic plane, but not the bladder, judged by magnetic resonance imaging (MRI). The use of preoperative chemoradiotherapy and the type of urologic resection were correlated with the status of the pathological circumferential resection margin (CRM) and local recurrence.\nA consecutive series of 126 men with rectal cancer threatening (44) or affecting (82) the prostatic plane on preoperative staging and operated with local curative intent between 1998 and 2010 was analysed. In patients who did not have chemoradiotherapy but had a preoperative threatened anterior margin the CRM-positive rate was 25.0%. In patients who did not have preoperative chemoradiotherapy but did have an affected margin, the CRM-positive rate was 41.7%. When preoperative radiotherapy was given, the respective CRM infiltration rates were 7.1 and 20.7%. In patients having preoperative chemoradiotherapy followed by prostatic resection the rate of CRM positivity was 2.4%. Partial prostatectomy after preoperative chemoradiotherapy resulted in a free anterior CRM in all cases, but intra-operative urethral damage occurred in 36.4% of patients who underwent partial prostatectomy, resulting in a postoperative urinary fistula in 18.2% of patients.\nQuestion: Rectal cancer threatening or affecting the prostatic plane: is partial prostatectomy oncologically adequate?\nAnswer:", " yes"], ["Abstract: A multicentre, retrospective study was conducted of patients with rectal cancer threatening or affecting the prostatic plane, but not the bladder, judged by magnetic resonance imaging (MRI). The use of preoperative chemoradiotherapy and the type of urologic resection were correlated with the status of the pathological circumferential resection margin (CRM) and local recurrence.\nA consecutive series of 126 men with rectal cancer threatening (44) or affecting (82) the prostatic plane on preoperative staging and operated with local curative intent between 1998 and 2010 was analysed. In patients who did not have chemoradiotherapy but had a preoperative threatened anterior margin the CRM-positive rate was 25.0%. In patients who did not have preoperative chemoradiotherapy but did have an affected margin, the CRM-positive rate was 41.7%. When preoperative radiotherapy was given, the respective CRM infiltration rates were 7.1 and 20.7%. In patients having preoperative chemoradiotherapy followed by prostatic resection the rate of CRM positivity was 2.4%. Partial prostatectomy after preoperative chemoradiotherapy resulted in a free anterior CRM in all cases, but intra-operative urethral damage occurred in 36.4% of patients who underwent partial prostatectomy, resulting in a postoperative urinary fistula in 18.2% of patients.\nQuestion: Rectal cancer threatening or affecting the prostatic plane: is partial prostatectomy oncologically adequate?\nAnswer:", " no"], ["Abstract: A multicentre, retrospective study was conducted of patients with rectal cancer threatening or affecting the prostatic plane, but not the bladder, judged by magnetic resonance imaging (MRI). The use of preoperative chemoradiotherapy and the type of urologic resection were correlated with the status of the pathological circumferential resection margin (CRM) and local recurrence.\nA consecutive series of 126 men with rectal cancer threatening (44) or affecting (82) the prostatic plane on preoperative staging and operated with local curative intent between 1998 and 2010 was analysed. In patients who did not have chemoradiotherapy but had a preoperative threatened anterior margin the CRM-positive rate was 25.0%. In patients who did not have preoperative chemoradiotherapy but did have an affected margin, the CRM-positive rate was 41.7%. When preoperative radiotherapy was given, the respective CRM infiltration rates were 7.1 and 20.7%. In patients having preoperative chemoradiotherapy followed by prostatic resection the rate of CRM positivity was 2.4%. Partial prostatectomy after preoperative chemoradiotherapy resulted in a free anterior CRM in all cases, but intra-operative urethral damage occurred in 36.4% of patients who underwent partial prostatectomy, resulting in a postoperative urinary fistula in 18.2% of patients.\nQuestion: Rectal cancer threatening or affecting the prostatic plane: is partial prostatectomy oncologically adequate?\nAnswer:", " maybe"], ["Abstract: To investigate the effectiveness of acupuncture in treating phonotraumatic vocal fold lesions.STUDY DESIGN/\nA total of 123 dysphonic individuals with benign vocal pathologies were recruited. They were given either genuine acupuncture (n\u00a0=\u00a040), sham acupuncture (n\u00a0=\u00a044), or no treatment (n\u00a0=\u00a039) for 6\u00a0weeks (two 30-minute sessions/wk). The genuine acupuncture group received needles puncturing nine voice-related acupoints for 30\u00a0minutes, two times a week for 6\u00a0weeks, whereas the sham acupuncture group received blunted needles stimulating the skin surface of the nine acupoints for the same frequency and duration. The no-treatment group did not receive any intervention but attended just the assessment sessions. One-hundred seventeen subjects completed the study (genuine acupuncture\u00a0=\u00a040; sham acupuncture\u00a0=\u00a043; and no treatment\u00a0=\u00a034), but only 84 of them had a complete set of vocal functions and quality of life measures (genuine acupuncture\u00a0=\u00a029; sham acupuncture\u00a0=\u00a033; and no-treatment\u00a0=\u00a022) and 42 of them with a complete set of endoscopic data (genuine acupuncture\u00a0=\u00a016; sham acupuncture\u00a0=\u00a015; and no treatment\u00a0=\u00a011).\nSignificant improvement in vocal function, as indicated by the maximum fundamental frequency produced, and also perceived quality of life, were found in both the genuine and sham acupuncture groups, but not in the no-treatment group. Structural (morphological) improvements were, however, only noticed in the genuine acupuncture group, which demonstrated a significant reduction in the size of the vocal fold lesions.\nQuestion: Is Acupuncture Efficacious for Treating Phonotraumatic Vocal Pathologies?\nAnswer:", " yes"], ["Abstract: To investigate the effectiveness of acupuncture in treating phonotraumatic vocal fold lesions.STUDY DESIGN/\nA total of 123 dysphonic individuals with benign vocal pathologies were recruited. They were given either genuine acupuncture (n\u00a0=\u00a040), sham acupuncture (n\u00a0=\u00a044), or no treatment (n\u00a0=\u00a039) for 6\u00a0weeks (two 30-minute sessions/wk). The genuine acupuncture group received needles puncturing nine voice-related acupoints for 30\u00a0minutes, two times a week for 6\u00a0weeks, whereas the sham acupuncture group received blunted needles stimulating the skin surface of the nine acupoints for the same frequency and duration. The no-treatment group did not receive any intervention but attended just the assessment sessions. One-hundred seventeen subjects completed the study (genuine acupuncture\u00a0=\u00a040; sham acupuncture\u00a0=\u00a043; and no treatment\u00a0=\u00a034), but only 84 of them had a complete set of vocal functions and quality of life measures (genuine acupuncture\u00a0=\u00a029; sham acupuncture\u00a0=\u00a033; and no-treatment\u00a0=\u00a022) and 42 of them with a complete set of endoscopic data (genuine acupuncture\u00a0=\u00a016; sham acupuncture\u00a0=\u00a015; and no treatment\u00a0=\u00a011).\nSignificant improvement in vocal function, as indicated by the maximum fundamental frequency produced, and also perceived quality of life, were found in both the genuine and sham acupuncture groups, but not in the no-treatment group. Structural (morphological) improvements were, however, only noticed in the genuine acupuncture group, which demonstrated a significant reduction in the size of the vocal fold lesions.\nQuestion: Is Acupuncture Efficacious for Treating Phonotraumatic Vocal Pathologies?\nAnswer:", " no"], ["Abstract: To investigate the effectiveness of acupuncture in treating phonotraumatic vocal fold lesions.STUDY DESIGN/\nA total of 123 dysphonic individuals with benign vocal pathologies were recruited. They were given either genuine acupuncture (n\u00a0=\u00a040), sham acupuncture (n\u00a0=\u00a044), or no treatment (n\u00a0=\u00a039) for 6\u00a0weeks (two 30-minute sessions/wk). The genuine acupuncture group received needles puncturing nine voice-related acupoints for 30\u00a0minutes, two times a week for 6\u00a0weeks, whereas the sham acupuncture group received blunted needles stimulating the skin surface of the nine acupoints for the same frequency and duration. The no-treatment group did not receive any intervention but attended just the assessment sessions. One-hundred seventeen subjects completed the study (genuine acupuncture\u00a0=\u00a040; sham acupuncture\u00a0=\u00a043; and no treatment\u00a0=\u00a034), but only 84 of them had a complete set of vocal functions and quality of life measures (genuine acupuncture\u00a0=\u00a029; sham acupuncture\u00a0=\u00a033; and no-treatment\u00a0=\u00a022) and 42 of them with a complete set of endoscopic data (genuine acupuncture\u00a0=\u00a016; sham acupuncture\u00a0=\u00a015; and no treatment\u00a0=\u00a011).\nSignificant improvement in vocal function, as indicated by the maximum fundamental frequency produced, and also perceived quality of life, were found in both the genuine and sham acupuncture groups, but not in the no-treatment group. Structural (morphological) improvements were, however, only noticed in the genuine acupuncture group, which demonstrated a significant reduction in the size of the vocal fold lesions.\nQuestion: Is Acupuncture Efficacious for Treating Phonotraumatic Vocal Pathologies?\nAnswer:", " maybe"], ["Abstract: It remains controversial whether there is a gender difference in survival of patients with resected non-small cell lung cancer.\nWe retrospectively analyzed 2770 patients (1689 men and 1081 women) with non-small cell lung cancer who underwent pulmonary resection between 1995 and 2005 at the National Cancer Center Hospital, Tokyo. A gender difference in survival was studied in all patients, in those divided according to histology or pathologic stage, and in propensity-matched gender pairs.\nThere were no differences in background, such as preoperative pulmonary function, operation procedures, or operative mortality. The proportions of adenocarcinoma and pathologic stage I in women were greater than those in men (93.6% vs 61.7% and 71.4% vs 58.6%, respectively) (P<.001). Overall 5-year survival of women was better than that of men (81% vs 70%, P<.001). In adenocarcinoma, the overall 5-year survival for women was better than that for men in pathologic stage I (95% vs 87%, P<.001) and in pathologic stage II or higher (58% vs 51%, P = .017). In non-adenocarcinoma, there was no significant gender difference in survival in pathologic stage I (P = .313) or pathologic stage II or higher (P = .770). The variables such as age, smoking status, histology, and pathologic stage were used for propensity score matching, and survival analysis of propensity score-matched gender pairs did not show a significant difference (P = .69).\nQuestion: Gender difference in survival of resected non-small cell lung cancer: histology-related phenomenon?\nAnswer:", " yes"], ["Abstract: It remains controversial whether there is a gender difference in survival of patients with resected non-small cell lung cancer.\nWe retrospectively analyzed 2770 patients (1689 men and 1081 women) with non-small cell lung cancer who underwent pulmonary resection between 1995 and 2005 at the National Cancer Center Hospital, Tokyo. A gender difference in survival was studied in all patients, in those divided according to histology or pathologic stage, and in propensity-matched gender pairs.\nThere were no differences in background, such as preoperative pulmonary function, operation procedures, or operative mortality. The proportions of adenocarcinoma and pathologic stage I in women were greater than those in men (93.6% vs 61.7% and 71.4% vs 58.6%, respectively) (P<.001). Overall 5-year survival of women was better than that of men (81% vs 70%, P<.001). In adenocarcinoma, the overall 5-year survival for women was better than that for men in pathologic stage I (95% vs 87%, P<.001) and in pathologic stage II or higher (58% vs 51%, P = .017). In non-adenocarcinoma, there was no significant gender difference in survival in pathologic stage I (P = .313) or pathologic stage II or higher (P = .770). The variables such as age, smoking status, histology, and pathologic stage were used for propensity score matching, and survival analysis of propensity score-matched gender pairs did not show a significant difference (P = .69).\nQuestion: Gender difference in survival of resected non-small cell lung cancer: histology-related phenomenon?\nAnswer:", " no"], ["Abstract: It remains controversial whether there is a gender difference in survival of patients with resected non-small cell lung cancer.\nWe retrospectively analyzed 2770 patients (1689 men and 1081 women) with non-small cell lung cancer who underwent pulmonary resection between 1995 and 2005 at the National Cancer Center Hospital, Tokyo. A gender difference in survival was studied in all patients, in those divided according to histology or pathologic stage, and in propensity-matched gender pairs.\nThere were no differences in background, such as preoperative pulmonary function, operation procedures, or operative mortality. The proportions of adenocarcinoma and pathologic stage I in women were greater than those in men (93.6% vs 61.7% and 71.4% vs 58.6%, respectively) (P<.001). Overall 5-year survival of women was better than that of men (81% vs 70%, P<.001). In adenocarcinoma, the overall 5-year survival for women was better than that for men in pathologic stage I (95% vs 87%, P<.001) and in pathologic stage II or higher (58% vs 51%, P = .017). In non-adenocarcinoma, there was no significant gender difference in survival in pathologic stage I (P = .313) or pathologic stage II or higher (P = .770). The variables such as age, smoking status, histology, and pathologic stage were used for propensity score matching, and survival analysis of propensity score-matched gender pairs did not show a significant difference (P = .69).\nQuestion: Gender difference in survival of resected non-small cell lung cancer: histology-related phenomenon?\nAnswer:", " maybe"], ["Abstract: The purpose of this study is to measure the accuracy and reliability of normally sighted, visually impaired, and blind pedestrians at making street crossing decisions using visual and/or auditory information.\nUsing a 5-point rating scale, safety ratings for vehicular gaps of different durations were measured along a two-lane street of one-way traffic without a traffic signal. Safety ratings were collected from 12 normally sighted, 10 visually impaired, and 10 blind subjects for eight different gap times under three sensory conditions: (1) visual plus auditory information, (2) visual information only, and (3) auditory information only. Accuracy and reliability in street crossing decision-making were calculated for each subject under each sensory condition.\nWe found that normally sighted and visually impaired pedestrians were accurate and reliable in their street crossing decision-making ability when using either vision plus hearing or vision only (P>0.05). Under the hearing only condition, all subjects were reliable (P>0.05) but inaccurate with their street crossing decisions (P<0.05). Compared to either the normally sighted (P = 0.018) or visually impaired subjects (P = 0.019), blind subjects were the least accurate with their street crossing decisions under the hearing only condition.\nQuestion: Are normally sighted, visually impaired, and blind pedestrians accurate and reliable at making street crossing decisions?\nAnswer:", " yes"], ["Abstract: The purpose of this study is to measure the accuracy and reliability of normally sighted, visually impaired, and blind pedestrians at making street crossing decisions using visual and/or auditory information.\nUsing a 5-point rating scale, safety ratings for vehicular gaps of different durations were measured along a two-lane street of one-way traffic without a traffic signal. Safety ratings were collected from 12 normally sighted, 10 visually impaired, and 10 blind subjects for eight different gap times under three sensory conditions: (1) visual plus auditory information, (2) visual information only, and (3) auditory information only. Accuracy and reliability in street crossing decision-making were calculated for each subject under each sensory condition.\nWe found that normally sighted and visually impaired pedestrians were accurate and reliable in their street crossing decision-making ability when using either vision plus hearing or vision only (P>0.05). Under the hearing only condition, all subjects were reliable (P>0.05) but inaccurate with their street crossing decisions (P<0.05). Compared to either the normally sighted (P = 0.018) or visually impaired subjects (P = 0.019), blind subjects were the least accurate with their street crossing decisions under the hearing only condition.\nQuestion: Are normally sighted, visually impaired, and blind pedestrians accurate and reliable at making street crossing decisions?\nAnswer:", " no"], ["Abstract: The purpose of this study is to measure the accuracy and reliability of normally sighted, visually impaired, and blind pedestrians at making street crossing decisions using visual and/or auditory information.\nUsing a 5-point rating scale, safety ratings for vehicular gaps of different durations were measured along a two-lane street of one-way traffic without a traffic signal. Safety ratings were collected from 12 normally sighted, 10 visually impaired, and 10 blind subjects for eight different gap times under three sensory conditions: (1) visual plus auditory information, (2) visual information only, and (3) auditory information only. Accuracy and reliability in street crossing decision-making were calculated for each subject under each sensory condition.\nWe found that normally sighted and visually impaired pedestrians were accurate and reliable in their street crossing decision-making ability when using either vision plus hearing or vision only (P>0.05). Under the hearing only condition, all subjects were reliable (P>0.05) but inaccurate with their street crossing decisions (P<0.05). Compared to either the normally sighted (P = 0.018) or visually impaired subjects (P = 0.019), blind subjects were the least accurate with their street crossing decisions under the hearing only condition.\nQuestion: Are normally sighted, visually impaired, and blind pedestrians accurate and reliable at making street crossing decisions?\nAnswer:", " maybe"], ["Abstract: Recently, orthostatic myoclonus (OM) has been suggested as a cause of gait impairment and unsteadiness in neurodegenerative diseases. The aim of this study was to investigate the frequency of orthostatic myoclonus, its clinical characteristics and the underlying associated neurological disorders.\nA retrospective analysis of clinical data and electromyogram surface recordings from subjects with unexplained unsteadiness/gait impairment was performed. Diagnosis of OM was made when a pattern of non-rhythmic bursts was observed (duration range 20-100 ms; bursts per second \u226416).\nAmong 93 subjects studied, OM was the most frequent disorder (n = 16; 17.2%), followed by orthostatic tremor (13.9%) and low frequency tremors during orthostatism (12.9%). All patients with OM complained about unsteadiness during orthostatism and/or during gait. Leg jerking was only observed by visual inspection during orthostatism in four subjects and two also presented falls. Eleven out of 16 patients (68.7%) with OM had an associated neurodegenerative disease, such as multiple system atrophy (n = 3) Parkinson's disease (n = 2), Alzheimer's disease (n = 2), mild cognitive impairment (n = 2) and normal pressure hydrocephalus (n = 2). Although four subjects showed improvement of orthostatic myoclonus with antimyoclonic treatment, the follow-up was not systematic enough to evaluate their therapeutic effect on OM.\nQuestion: Orthostatic myoclonus: an underrecognized cause of unsteadiness?\nAnswer:", " yes"], ["Abstract: Recently, orthostatic myoclonus (OM) has been suggested as a cause of gait impairment and unsteadiness in neurodegenerative diseases. The aim of this study was to investigate the frequency of orthostatic myoclonus, its clinical characteristics and the underlying associated neurological disorders.\nA retrospective analysis of clinical data and electromyogram surface recordings from subjects with unexplained unsteadiness/gait impairment was performed. Diagnosis of OM was made when a pattern of non-rhythmic bursts was observed (duration range 20-100 ms; bursts per second \u226416).\nAmong 93 subjects studied, OM was the most frequent disorder (n = 16; 17.2%), followed by orthostatic tremor (13.9%) and low frequency tremors during orthostatism (12.9%). All patients with OM complained about unsteadiness during orthostatism and/or during gait. Leg jerking was only observed by visual inspection during orthostatism in four subjects and two also presented falls. Eleven out of 16 patients (68.7%) with OM had an associated neurodegenerative disease, such as multiple system atrophy (n = 3) Parkinson's disease (n = 2), Alzheimer's disease (n = 2), mild cognitive impairment (n = 2) and normal pressure hydrocephalus (n = 2). Although four subjects showed improvement of orthostatic myoclonus with antimyoclonic treatment, the follow-up was not systematic enough to evaluate their therapeutic effect on OM.\nQuestion: Orthostatic myoclonus: an underrecognized cause of unsteadiness?\nAnswer:", " no"], ["Abstract: Recently, orthostatic myoclonus (OM) has been suggested as a cause of gait impairment and unsteadiness in neurodegenerative diseases. The aim of this study was to investigate the frequency of orthostatic myoclonus, its clinical characteristics and the underlying associated neurological disorders.\nA retrospective analysis of clinical data and electromyogram surface recordings from subjects with unexplained unsteadiness/gait impairment was performed. Diagnosis of OM was made when a pattern of non-rhythmic bursts was observed (duration range 20-100 ms; bursts per second \u226416).\nAmong 93 subjects studied, OM was the most frequent disorder (n = 16; 17.2%), followed by orthostatic tremor (13.9%) and low frequency tremors during orthostatism (12.9%). All patients with OM complained about unsteadiness during orthostatism and/or during gait. Leg jerking was only observed by visual inspection during orthostatism in four subjects and two also presented falls. Eleven out of 16 patients (68.7%) with OM had an associated neurodegenerative disease, such as multiple system atrophy (n = 3) Parkinson's disease (n = 2), Alzheimer's disease (n = 2), mild cognitive impairment (n = 2) and normal pressure hydrocephalus (n = 2). Although four subjects showed improvement of orthostatic myoclonus with antimyoclonic treatment, the follow-up was not systematic enough to evaluate their therapeutic effect on OM.\nQuestion: Orthostatic myoclonus: an underrecognized cause of unsteadiness?\nAnswer:", " maybe"], ["Abstract: Older adults (OA) with advanced cancer (AC) undergoing phase I clinical trials (PICT) have poor prognosis. There are no studies which describe symptoms experienced by OA.\nRetrospective chart review of PICT participants>60 years. OA were compared by age (>65 vs 60-65) and by number of symptoms (>3 vs \u22643).\nN = 56. Mean age = 67.09; 48.21% female. Median life-expectancy = 5 months (interquartile range = 2-9 months); 80.36% had pain; of those 64% without pain scale. Most did not have interdisciplinary professionals or hospice referrals. Older adults with>3 symptoms had more admissions (37.5% vs 14.29%; P = .0335), complications (46.43% vs 16.07%; P = .0026), and greater decline in functional status (24 participants>3 symptoms vs 8; P = .0173). There were no significant differences comparing OA by age.\nQuestion: Do symptoms matter when considering patients for phase I clinical trials?\nAnswer:", " yes"], ["Abstract: Older adults (OA) with advanced cancer (AC) undergoing phase I clinical trials (PICT) have poor prognosis. There are no studies which describe symptoms experienced by OA.\nRetrospective chart review of PICT participants>60 years. OA were compared by age (>65 vs 60-65) and by number of symptoms (>3 vs \u22643).\nN = 56. Mean age = 67.09; 48.21% female. Median life-expectancy = 5 months (interquartile range = 2-9 months); 80.36% had pain; of those 64% without pain scale. Most did not have interdisciplinary professionals or hospice referrals. Older adults with>3 symptoms had more admissions (37.5% vs 14.29%; P = .0335), complications (46.43% vs 16.07%; P = .0026), and greater decline in functional status (24 participants>3 symptoms vs 8; P = .0173). There were no significant differences comparing OA by age.\nQuestion: Do symptoms matter when considering patients for phase I clinical trials?\nAnswer:", " no"], ["Abstract: Older adults (OA) with advanced cancer (AC) undergoing phase I clinical trials (PICT) have poor prognosis. There are no studies which describe symptoms experienced by OA.\nRetrospective chart review of PICT participants>60 years. OA were compared by age (>65 vs 60-65) and by number of symptoms (>3 vs \u22643).\nN = 56. Mean age = 67.09; 48.21% female. Median life-expectancy = 5 months (interquartile range = 2-9 months); 80.36% had pain; of those 64% without pain scale. Most did not have interdisciplinary professionals or hospice referrals. Older adults with>3 symptoms had more admissions (37.5% vs 14.29%; P = .0335), complications (46.43% vs 16.07%; P = .0026), and greater decline in functional status (24 participants>3 symptoms vs 8; P = .0173). There were no significant differences comparing OA by age.\nQuestion: Do symptoms matter when considering patients for phase I clinical trials?\nAnswer:", " maybe"], ["Abstract: Knowing the collaterals is essential for a spleen-preserving distal pancreatectomy with resection of the splenic vessels.\nTo ascertain the sources of the blood supply to the spleen after a spleen-preserving distal pancreatectomy with resection of the splenic vessels.\nPerfusion of the cadaveric left gastric and right gastroepiploic arteries with methylene blue after occlusion of all the arteries except the short gastric arteries (n=10). Intraoperative color Doppler ultrasound was used for the evaluation of the hilar arterial blood flow at distal pancreatectomy (n=23) after 1) clamping of the splenic artery alone, 2) clamping of the splenic and left gastroepiploic arteries and 3) clamping of the splenic and short gastric arteries. CT angiography of the gastric and splenic vessels before and after a spleen-preserving distal pancreatectomy (n=10).\nPerfusion of the cadaveric arteries revealed no effective direct or indirect (through the submucous gastric arterial network) communication between the left gastric and the branches of the short gastric arteries. In no case did intraoperative color Doppler ultrasound detect any hilar arterial blood flow after the clamping of the splenic and left gastroepiploic arteries. The clamping of the short gastric arteries did not change the flow parameters. In none of the cases did a post-spleen-preserving distal pancreatectomy with resection of the splenic vessels CT angiography delineate the short gastric vessels supplying the spleen. In all cases, the gastroepiploic arcade was the main arterial pathway feeding the spleen.\nQuestion: Spleen-preserving distal pancreatectomy with resection of the splenic vessels. Should one rely on the short gastric arteries?\nAnswer:", " yes"], ["Abstract: Knowing the collaterals is essential for a spleen-preserving distal pancreatectomy with resection of the splenic vessels.\nTo ascertain the sources of the blood supply to the spleen after a spleen-preserving distal pancreatectomy with resection of the splenic vessels.\nPerfusion of the cadaveric left gastric and right gastroepiploic arteries with methylene blue after occlusion of all the arteries except the short gastric arteries (n=10). Intraoperative color Doppler ultrasound was used for the evaluation of the hilar arterial blood flow at distal pancreatectomy (n=23) after 1) clamping of the splenic artery alone, 2) clamping of the splenic and left gastroepiploic arteries and 3) clamping of the splenic and short gastric arteries. CT angiography of the gastric and splenic vessels before and after a spleen-preserving distal pancreatectomy (n=10).\nPerfusion of the cadaveric arteries revealed no effective direct or indirect (through the submucous gastric arterial network) communication between the left gastric and the branches of the short gastric arteries. In no case did intraoperative color Doppler ultrasound detect any hilar arterial blood flow after the clamping of the splenic and left gastroepiploic arteries. The clamping of the short gastric arteries did not change the flow parameters. In none of the cases did a post-spleen-preserving distal pancreatectomy with resection of the splenic vessels CT angiography delineate the short gastric vessels supplying the spleen. In all cases, the gastroepiploic arcade was the main arterial pathway feeding the spleen.\nQuestion: Spleen-preserving distal pancreatectomy with resection of the splenic vessels. Should one rely on the short gastric arteries?\nAnswer:", " no"], ["Abstract: Knowing the collaterals is essential for a spleen-preserving distal pancreatectomy with resection of the splenic vessels.\nTo ascertain the sources of the blood supply to the spleen after a spleen-preserving distal pancreatectomy with resection of the splenic vessels.\nPerfusion of the cadaveric left gastric and right gastroepiploic arteries with methylene blue after occlusion of all the arteries except the short gastric arteries (n=10). Intraoperative color Doppler ultrasound was used for the evaluation of the hilar arterial blood flow at distal pancreatectomy (n=23) after 1) clamping of the splenic artery alone, 2) clamping of the splenic and left gastroepiploic arteries and 3) clamping of the splenic and short gastric arteries. CT angiography of the gastric and splenic vessels before and after a spleen-preserving distal pancreatectomy (n=10).\nPerfusion of the cadaveric arteries revealed no effective direct or indirect (through the submucous gastric arterial network) communication between the left gastric and the branches of the short gastric arteries. In no case did intraoperative color Doppler ultrasound detect any hilar arterial blood flow after the clamping of the splenic and left gastroepiploic arteries. The clamping of the short gastric arteries did not change the flow parameters. In none of the cases did a post-spleen-preserving distal pancreatectomy with resection of the splenic vessels CT angiography delineate the short gastric vessels supplying the spleen. In all cases, the gastroepiploic arcade was the main arterial pathway feeding the spleen.\nQuestion: Spleen-preserving distal pancreatectomy with resection of the splenic vessels. Should one rely on the short gastric arteries?\nAnswer:", " maybe"]]