Commit 064cd20d authored by Gustaf Ahdritz's avatar Gustaf Ahdritz
Browse files

Add note on AlphaFold-Gap

parent a1cf7454
...@@ -149,6 +149,12 @@ Powerusers can choose to tweak these settings in ...@@ -149,6 +149,12 @@ Powerusers can choose to tweak these settings in
`openfold/model/primitives.py`. For more information on the LMA algorithm, `openfold/model/primitives.py`. For more information on the LMA algorithm,
see the aforementioned Staats & Rabe preprint. see the aforementioned Staats & Rabe preprint.
Input FASTA files containing multiple sequences are treated as complexes. In
this case, the inference script runs AlphaFold-Gap, a hack proposed
[here](https://twitter.com/minkbaek/status/1417538291709071362?lang=en), using
the specified stock AlphaFold/OpenFold parameters (NOT AlphaFold-Multimer). To
run inference with AlphaFold-Multimer, use the `multimer` branch instead.
### Training ### Training
To train the model, you will first need to precompute protein alignments. To train the model, you will first need to precompute protein alignments.
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